I'd recommend seeing a doctor if it's just come on suddenly - it might be something easily treatable or that needs medical attention. In the meantime you could put bed pads on the bed so you don't have to change the sheets 2/3 times a night, that seems excessive. Put 3 mats down and if you wake up wet (which you might not if it's your wife that wakes now) you can peel one off and go to the next one. If you don't wake when you wet then in the morning you can just wash the top mat. The other temporary solution I guess (and this addresses the messing issue too) is to wear a diaper to bed, but that might not be an area you're willing to go to. Hope that helps. Anna xx